|
|
Tilmicosin
[ SYNONYMS ] : 20-Deoxy-20-(3,5-dimethylpiperidin-1-yl)-desmycosin
[ Chemical Name ] :
Tilmicosin (IUPAC name): (10E, 12E)-(3R,4S,5S,6R,8R,14R,15R)-14-(6-deoxy-2,3-di-O-methyl-b-d-allo-hexopyranosyoxymethyl)-5-(3,6-dideoxy-3-dimethylamino-b-d-gluco-hexapyranosyloxy)-6-[2-(cis-3,5-dimethyl-piperidino)ethyl]-3-hydroxy-4,8,12-trimethyl-9-oxoheptadeca-10,12-dien-15-olide Chemical Abstracts Services Name: tylosin, 4A-O-de(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-20-deoxy-20-(3,5-dimethyl-1-piperidinyl)-(20(cis: trans))
[CAS Number ] : 108050-54-0
[ Structural Formula ] :

[ Molecular Weight ] : 869.15
[ SPECIFICATION: ] :
USP24 see a COA
Analysis Item
|
Standard
|
Analysis Results
|
Appearnce
|
White or almost white powder
|
almost white powder
|
Identification
|
Pass
|
Pass
|
Content ( on
Dried basis )
|
85% Min
|
94.2%
|
Trans-isomer
|
12.0~18.0%
|
13.10%
|
| Cis-isomer |
82.0~88.0% |
86.9%
|
Moisture
|
5.0% Max
|
2.2%
|
Related Compounds
|
Pass
|
Pass
|
Individual Impurities
|
3% Max
|
1.3%
|
Total Impurities
|
10% max
|
4.3%
|
Infrared Spectrum
|
Pass
|
Pass
|
[ PACKING ] : as per required
[ USES & STORAGE ] : Uses: Tilmicosin is a macrolide antibiotic developed for veterinary use. It is recommended for treatment and prevention of pneumonia in cattle, sheep and pigs, associated with Pasteurella haemolytica, P. multocida, Actinobacillus pleuropneumoniae, mycoplasma species and other microorganisms found sensitive to this compound.
|